Sir Henry Solomon Wellcome FRS (August 21, 1853 – July 25, 1936) was a British pharmaceutical entrepreneur.
He founded the pharmaceutical company Burroughs Wellcome & Company with his colleague Silas Burroughs in 1880, which is one of the four large companies to eventually merge to form GlaxoSmithKline.
In addition, he left a large amount of capital for charitable work in his will, which was used to form the Wellcome Trust, one of the world's largest medical charities.
He was also a keen collector of medical artifacts which are now displayed at the Wellcome Collection.