Issac Luke (born 29 May 1987) is a New Zealand professional rugby league footballer who plays as a hooker for the St George Illawarra Dragons in the NRL, and New Zealand at international level.
He previously played for the South Sydney Rabbitohs in the National Rugby League.
He was a part of the Rabbitohs squad that won the 2014 NRL Premiership, however despite being named as starting hooker, was ruled out for the final due to suspension.
Luke is a member of the World Cup-winning New Zealand team that beat Australia in the 2008 Final.