Jeffrey James Weise (August 8, 1988 – March 21, 2005) was an American teenage mass murderer and spree killer, who was a student at Red Lake Senior High School in Red Lake, Minnesota, located on the reservation of the Ojibwe people.
He murdered nine people in a shooting spree on March 21, 2005.
He killed his grandfather and his grandfather's companion before going to the reservation high school, where he murdered seven more people and wounded five others.
He committed suicide before being captured by the police.
Weise struggled in school due to frequent relocations, bullying, disruptions in his personal life and truancy.
In May and June 2004, Weise tried twice to commit suicide and was briefly hospitalized.
He was under treatment for depression, and had been prescribed Prozac as an anti-depressant.
His case revived the public discussion about the use of Prozac for children and adolescents; the US Food and Drug Administration had published a warning about it in October 2004 as a factor in increased suicides and violence among youths.