Djénébou Sissoko (born June 27, 1982 in San) is a Malian women's basketball player.
Sissoko represented Mali, and competed as part of the women's national basketball team at the 2008 Summer Olympics in Beijing.
During the tournament, she scored a total of twenty-four points and thirty-two rebounds, including thirteen against the Czech Republic, in five group play games.
Sissoko is also a member of Djoliba AC women's basketball team in Bamako.