Among other things, Chappuzeau played a substantial part in "discovering" Molière when he gave his travelling troupe a glowing review in his book Lyon dans son lustre in 1656.
Chappuzeau is credited with a number of "firsts," including being the first writer to introduce satire to French farce, and the first to set a play in China.
Later, he composed Tavernier's famous travel guides from notes and dictation, though this task seems to have been forced upon him, much against his will, by the King (Louis XIV).
Chappuzeau also wrote sermons, odes, dictionaries, and geographical books, and was still working on his Nouveau Dictionaire almost up to his death.