Mame Seydina Issa Laye Thiaw (born 12 October 1992), commonly known as Issa Thiaw, is a Senegalese professional footballer who plays as a midfielder for Finnish Veikkausliiga side KuPS.
Issa started his career at RS Yoff from Senegal, then played in Romania for various Liga II and Liga III clubs such as: Voin?a Sibiu, FC Cisnadie, Unirea Alba Iulia and ?oimii Pâncota.
After a Liga I promotion with Sepsi Sfântu Gheorghe, he made his debut in the first league on 16 July 2017, in a 0-1 defeat against Astra Giurgiu.