At the club level, Ruggeri's most successful stint was with Argentine club River Plate, where he won the 1986 Copa Libertadores (also the club's first win in this tournament) the 1986 Copa Interamericana and the 1986 Intercontinental Cup.
Known for his rough style of play when marking opposing players and aerial ability, Ruggeri is considered one of the all-time best defenders to come out of Argentina.
Following his retirement as a player, Ruggeri turned to managing, where he held posts in Argentina, Mexico and Spain.
His last job as a manager was in 2006 with Argentine club San Lorenzo.
Since then, Ruggeri went on to have a career on Argentine television, as commentator on football shows.
He is currently a member of 90 Minutos de FĂştbol, which airs in Fox Sports Latin America.