Sebastian Kindelán y O’Regan, also called Sebastián de Kindelán y Oregón, (30 December 1757 – 4 May 1826) was a colonel in the Spanish Army who served as governor of East Florida (11 June 1812 – 3 June 1815) and of Santo Domingo during the Second Spanish period (1818–1821), as well as provisional governor of Cuba (1822–1823).