Setsuko Karasuma (?? ???, Karasuma Setsuko) is an actress and model born on 3 February 1955 in Otsu, Shiga Prefecture, Japan.
She attended Chukyo University, but left before finishing.
She is employed by the From First Production talent agency.
Karasuma made her debut as a Clarion Girl in 1980, moving quickly into the gravure idol scene.
Her debut as a film actress came as she got the lead role in the 1980 adaptation of the Hiroyuki Itsuki novel Four Seasons·Natsuko (??·???, Shiki·Natsuko).