Karl Vilhelm Zetterstéen (18 August 1866 – 1953) was a Swedish orientalist.
Born in Orsa, Dalarna, Zetterstéen began his studies at Uppsala University in 1884, became a Ph.D.
and docent of Semitic languages in 1895.
He was acting professor of Oriental languages at Lund University 1895-1904 and professor of Semitic languages in Uppsala 1904-1931.
He also studied under Eduard Sachau at the University of Berlin.
As a semitist, Zetterstéen was foremost an Arabic philologist, but he was also well-oriented in non-Semitic languages such as Persian, Turkish and Nubian.
Beside a large number of text editions and studies, he published a Swedish translation of the Qur'an, a number of popular works, and wrote several articles in the Nordisk familjebok.