Santiago Giraldo Salazar (American Spanish: [san'tja?o xi'?aldo sala'sa?], born 27 November 1987) is a Colombian professional tennis player.
He plays on the ATP tour and represents Colombia in the Davis Cup competition.
His best tournament result is reaching the final in the 2014 Barcelona Open Banc Sabadell.
He is the highest-ranked tennis player in Colombia's history, with a career-high singles ranking of 28th in the world, and 77th in doubles.
Throughout his career he has beaten several ex-number-one players such as Lleyton Hewitt, Juan Carlos Ferrero, and Andy Murray as well as some top-ten players such as Jo-Wilfried Tsonga, Kei Nishikori, Marin Cilic, Milos Raonic, Dominic Thiem, Gilles Simon, Jürgen Melzer, Rainer Schüttler, Tommy Robredo, Janko Tipsarevic, and Nicolás Lapentti.
He has beaten golden-generation players from Argentinian tennis such as Gastón Gaudio, Guillermo Cañas, Mariano Puerta, Juan Martin del Potro, and David Nalbandian.