Anna Isabella Gonzaga (12 February 1655 – 11 August 1703), was a Duchess consort of Mantua and Montferrat and heir of the Duchy of Guastalla, including Luzzara and Reggiolo; married in 1671 to Ferdinando Carlo Gonzaga, Duke of Mantua and Montferrat.
She was the regent of Mantua during the War of the Spanish Succession.