Jean Nageotte, Date of Birth, Place of Birth, Date of Death

    

Jean Nageotte

French neuroanatomist, neurologist and neuropathologist

Date of Birth: 08-Feb-1866

Place of Birth: Dijon, Bourgogne-Franche-Comté, France

Date of Death: 22-Jul-1948

Profession: professor, neurologist, anatomist

Nationality: France

Zodiac Sign: Aquarius


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About Jean Nageotte

  • Jean Nageotte (8 February 1866 – 22 July 1948) was a French neuroanatomist born in Dijon.
  • He obtained his medical degree in Paris in 1893, and afterwards was associated with the HĂ´pital BicĂŞtre and SalpĂŞtrière.
  • He succeeded Louis-Antoine Ranvier (1835–1922) in what then became the chair of comparative histology at the Collège de France.
  • Nageotte specialized in anatomical research of the nervous system, and in his work stressed the importance of microscopic anatomy.
  • He performed research of nerve fibers and the myelin sheath, and conducted studies involving connective tissue.
  • He provided a description of boutons terminaux (terminal buttons) of spinal nerves, and did extensive work with nerve grafting.
  • In addition he investigated tabes dorsalis, and with Joseph Babinski (1857–1932), the Babinski-Nageotte syndrome was described.
  • This syndrome is a complex of symptoms associated with medullary lesions.
  • He documented this disorder in a treatise called HĂ©miasynergie, latĂ©ropulsion et miosis bulbaire.
  • Also with Babinski, he co-wrote a book on cerebrospinal fluid. In his 1910 article, he surmised that glial cells behaves like an endocrine organ and secretes several molecules into the blood.
  • Albeit the importance of this proposal had not been recognized in his time, today we know that glias have neurotransmitter receptors and even more, release neurotransmitters with similar mechanisms as neurons. Other eponyms associated with Jean Nageotte: Nageotte cells: mononuclear cells found in the cerebrospinal fluid; 1 or 2 Nageotte cells per cubic millimeter are typically found in healthy individuals, but larger numbers of these cells are an indication of disease. Nageotte's radicular nerve: Nageotte placed the initial lesion of tabes dorsalis in the root component of the radicular nerve.

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