Sir Thomas Francis "Frank" Little KBE (30 November 1925 – 7 April 2008) was an Australian bishop.
He was the sixth Roman Catholic Archbishop of Melbourne.
He was appointed by Pope Paul VI on 1 July 1974 and retired in 1996; he was succeeded by the Most Reverend George Pell (as he was styled at the time).
On retirement he was styled Archbishop Emeritus in the Archdiocese of Melbourne.
The Royal Commission into Institutional Responses to Child Sexual Abuse found that Little had led a culture of secrecy in the Melbourne archdiocese designed to hide complaints against several priests and protect the church's reputation from scandal.