He played parts of two Major League Baseball (MLB) seasons for the Chicago Cubs (1993–94), playing four different positions.
He batted and threw right-handed.
He was the American Association MVP in 1993, leading the league with 32 home runs and 115 runs batted in.
In the majors, Zambrano was a career .263 hitter (35-133), with six home runs, 20 RBI, 18 runs, seven doubles, and two stolen bases in 75 games.
Zambrano's nephew, Rougned Odor, plays in MLB.