Giacomo Mancini (21 April 1916 – 8 April 2002) was an Italian Socialist Party politician.
He was minister of health (1963-1964) in the Government of Italy.
He served in the cabinet of Prime Minister Aldo Moro.
He served in the Chamber of Deputies of Italy in Legislature I (1948–1953), Legislature II (1953–1958), Legislature III (1958–1963), Legislature IV (1963–1968), Legislature V (1968–1972), Legislature VI (1972–1976), Legislature VII (1976–1979), Legislature VIII (1979–1983), Legislature IX and Legislature X