Adrien Sibomana (born Bukeye, Muramvya on 4 September 1953) was the prime minister of Burundi from 19 October 1988 until 10 July 1993.
He was a member of UPRONA.
He is an ethnic Hutu and was appointed by the Tutsi President Pierre Buyoya in an unsuccessful attempt to appease Hutus by giving a few high government posts to them.
Sibomana was the first Hutu prime minister since 1973 and previously had been governor of Muramvya Province.