Leopoldo Di Girolamo (born 11 August 1951 in Montorio al Vomano) is an Italian politician.
He is a member of the Democratic Party and was elected at the Senate of the Republic for two legislatures (XIV, XVI) and at the Chamber of Deputies for the XV legislature in 2006.Di Girolamo served as Mayor of Terni for two terms (2009-2018) and President of the Province of Terni from 2014 to 2016.