Yevdokiya Borisovna Yusupova (Russian: ??????´? ????´????? ???´????; May 5 (NS: May 16) 1743, Moscow – July 19 (NS: July 8) 1780, Saint Petersburg), was a Duchess consort of Courland.
She married the Duke of Courland, Peter von Biron, on March 6, 1774 in Mitava (Mittau).