She competed in the 100 m event at the 2012 Summer Olympics and advanced to the semifinals.
At the 2016 Summer Olympics she was eliminated in the heats of the 100 m, 200 m and 4×100 m events.
At the 2010 Asian Indoor Athletics Championships, she won a bronze medal in the 60 m and a silver at the 4×400 m relay.
Safronova won four medals at the Asian Games in 2014–2018, two individual and two in the 4×100 m relay.Her mother Irina was a hurdler, her brother Maxim is a high jumper.
Her husband Konstantin Safronov competed internationally in the long jump.