Isabelle Marie Ndjole Assouho (born November 27, 1936, in Kribi) is a Cameroonian politician.
She was elected senator for the East Region during the first senatorial elections held on April 14, 2013.As a university professor, she was chairman of the board of Yaounde and was replaced by Aminatou Ahidjo on June 29, 2016.For five years, she was State Secretary at the Ministry of National Education (now the Ministry of Secondary Education).