Ashikaga Motouji (????) (1340–1367) was a warrior of the Nanboku-cho period.
The fourth son of shogun Ashikaga Takauji, he was the first of a dynasty of five Kanto kubo, Kamakura-based representatives in the vital Kamakura-fu of Kyoto's Ashikaga regime.
Meant to stabilize a volatile situation in the Kanto, a region where many warrior clans wanted the return of the shogunate from Kyoto back to Kamakura, the dynasty he started almost immediately developed the ambition to usurp the shogunate, becoming a serious headache for the central government.
Motouji was the only kubo who always remained loyal to the Kyoto government.
During the Kanno disturbance, a historical episode with serious repercussions on his life, he tried to reconcile his father with his uncle Ashikaga Tadayoshi and, after his father's demise, he collaborated with his elder brother, shogun Ashikaga Yoshiakira, to stabilize the shogunate.