Luis Barrios Tassano (San Carlos, Uruguay, 26 August 1935 – Montevideo, 15 December 1991) was a Uruguayan lawyer and diplomat.
A man of the Colorado Party, when the democracy came back in 1985 he was appointed Ambassador to Argentina.
He further undertook a decisive action in order to establish bilateral relations with the People's Republic of China.
Later he was appointed Foreign Minister (1988–1990).