Ann Elizabeth Isham (January 25, 1862 – April 15, 1912) was a passenger aboard the RMS Titanic.
She was one of five female first-class passengers (four women and one child) to die when the ship sank.
An undocumented legend states she probably died because she did not want to leave behind her Great Dane; a woman was reportedly sighted in the water with her arms frozen around a dog.