Alexander George Karczmar (May 9, 1917 – August 17, 2017), was a Polish-American neuroscientist and academician.
His academic career culminated with 30 years tenure (1956–1986) as professor and chairman of the Department of Pharmacology and Experimental Therapeutics at Loyola University of Chicago Medical Center, and director of its Institute for Mind, Drugs and Behavior.
He is widely recognized for his experimental research, almost all of which is devoted to the cholinergic system, both central and peripheral, and its autonomic and mental functions, including its control of various human and animal behaviors.
From the 1970s he explored the existence and the nature of the "self".