John Cross Anyogu (11 March 1898 – 5 July 1967) was a Nigerian clergyman who, on 9 June 1957, became the first member of his Igbo community to be consecrated a Roman Catholic bishop.
He was also the first Igbo to be ordained a priest in 1930 and the first bishop of the Roman Catholic Diocese of Enugu which was created in 1963, the year of his installation.
Through his efforts Enugu became a very important Catholic mission centre overseeing several thousand Christians in and around the town.
His parish has the largest concentration of Catholics in Nigeria, second only to Owerri parish.