Charleston Hughes (born December 14, 1983) is a professional Canadian football defensive lineman for the Saskatchewan Roughriders of the Canadian Football League.
He was signed by the Calgary Stampeders as a street free agent in 2008 and won two Grey Cup championships over his ten-year tenure with the club (in 2008 and 2014).
He is a five-time CFL All-Star and seven-time division All-Star.
He was also named the West Division's Most Outstanding Defensive Player in 2013.
He played college football for Northwood.
Hughes has also been a member of the Philadelphia Eagles (NFL) and briefly the Hamilton Tiger-Cats.