Shrinivas Ramchandra Kulkarni (born 1956) is a US-based astronomer born and raised in India.
He is currently a professor of astronomy and planetary science at California Institute of Technology, and he serves as director of Caltech Optical Observatory (COO) at California Institute of Technology, in which capacity he oversees the Palomar and Keck among other telescopes.
He is the recipient of a number of awards and honours.
Kulkarni is the brother of Sudha Murthy and brother-in-law of Narayana Murthy, founder of Infosys.
He has been the Jury Chair for the Infosys Prize for the discipline of Physical Sciences since 2009.