Franck Emmanuel Issoze-Ngondet (born 2 April 1961) is a Gabonese diplomat and politician who is a former Prime Minister of Gabon.
A career diplomat, Issoze-Ngondet was Gabon's Permanent Representative to the United Nations from August 2008 to January 2009.
Afterwards he served in the government of Gabon as Minister of Energy from January 2009 to June 2009 and then briefly as Minister of Relations with Parliament in mid-2009.
He was again appointed as Permanent Representative to the UN in November 2009.
In March 2010, Issoze-Ngondet was the President of the United Nations Security Council.
Issoze-Ngondet was appointed as Minister of Foreign Affairs on 28 February 2012.
After more than four years in that post, he was appointed as Prime Minister on 28 September 2016.