Kimishige "Kimi" Ishizaka (?? ??, Ishizaka Kimishige, 3 December 1925 – 6 July 2018) was a Japanese immunologist who, with his wife Terako Ishizaka, discovered the antibody class Immunoglobulin E (IgE) in 1966–1967.
Their work was regarded as a major breakthrough in the understanding of allergy.
He was awarded the 1973 Gairdner Foundation International Award and the 2000 Japan Prize for his work in immunology.