María Teresa Castillo (October 15, 1908 – June 22, 2012) was a Venezuelan journalist, politician, political activist, human rights activist, and cultural entrepreneur.
She was the founder of the Caracas Athenaeum, a leading cultural institution which promotes the arts of Caracas.
She also served as the president of Caracas Athenaeum from 1958 until her death in 2012.
Castillo, a proponent of human rights, also played a major role in the formation of Amnesty International's Venezuelan chapter in 1978.