Sebastiano Mannironi (22 July 1930 – 11 June 2015) was an Italian weightlifter who competed at the 1956, 1960 and 1964 Summer Olympics; he won a bronze medal in 1960 and finished fifth in 1964.
Between 1953 and 1966 Mannironi won 14 medals at European and World Championships, including a gold at the 1961 European Championships, and set one world record, in the snatch in 1958.