Alles (November 26, 1901 – January 21, 1963), was an American chemist and pharmacologist who did extensive research on the isolation and properties of insulin for the treatment of diabetics.
He is also credited with discovering and publishing the physiological effects of amphetamine and methylenedioxyamphetamine (MDA).
He is the first person to have prepared amphetamine sulfate, although not the amphetamine molecule.
Alles first reported the physiological properties of amphetamine as a synthetic analog of ephedrine, and therefore received credit for this discovery.
He enjoyed large royalties from Smith, Kline & French (SKF) because he sold his patent rights for amphetamine to the company and it enjoyed large sales.
Several popular products sold by SKF contained amphetamine, including Benzedrine pills and inhalers, Dexedrine pills and Dexamyl tablets.
Counterfeit drugs such as Profetamine (a generic form of amphetamine sulfate) appeared, aiming to circumvent Alles' 'weak' patent.