Isidore Mvouba (born 1954) is a Congolese politician who was Prime Minister of Congo-Brazzaville from 2005 to 2009.
He is a member of the Congolese Labour Party (PCT, or Parti congolais du travail) and held key positions under President Denis Sassou Nguesso beginning in 1997.
Mvouba was Director of the Cabinet of the Head of State from 1997 to 1999, Minister of Transport from 1999 to 2005 (with responsibility for coordinating government action beginning in 2002), and Prime Minister from January 2005 to September 2009.
After his post of Prime Minister was eliminated, he instead served as Minister of State for Transport, responsible for coordinating ministries relating to infrastructure, from 2009 to 2012.
Subsequently he was Minister of State for Industrial Development from 2012 to 2016.
He has been President of the National Assembly since 2017.