Ruqayyah bint Al-?usayn (Arabic: ?????? ????? ???????????) (born on the 20th of Rajab, 56 AH – 5 Rabi' al-thani, 60 / 61 AH or 676 CE; died on the 13th of Safar, 60 / 61 AH or 680 / 681 CE), was the daughter of Husayn ibn Ali and Rubab bint Imra al-Qais ibn Adi bin Aws.
Her brothers included Ali Zaynul-Abidin, Ali al-Akbar, and Ali al-Asghar.
Her sisters included Fatimah as-Sughra and Fatimah al-Kubra, with the latter also being called 'Sakinah'.