She was principal investigator of the Near-Earth Asteroid Tracking (NEAT) program of NASA's Jet Propulsion Laboratory.
(Some sources give her name as Eleanor Kay Helin.) She retired in 2002, and then died in 2009, at 76 years old.
Helin is a prolific discoverer of minor planets (see list) and several comets, including periodic comets 111P/Helin–Roman–Crockett, 117P/Helin–Roman–Alu and 132P/Helin–Roman–Alu.
She is credited as the discoverer of the object now known as both asteroid 4015 Wilson–Harrington and comet 107P/Wilson–Harrington.
Although Wilson and Harrington preceded her by some decades, their observations did not establish an orbit for the object, while her rediscovery did.
Helin discovered or co-discovered 903 asteroids and several comets.