Isaac Mohammed Alfa (born 15 September 1950 in Inye, Kogi State, Nigeria) is a retired Nigerian Air Force Air Marshal, former Chief of Air Staff, and Senator from Kogi State.
In 2003 he contested the governorship of Kogi State.
In July 2016, he was elected to the Senate of Nigeria, for the Nigerian National Assembly delegation from Kogi.
However on January 10 2007 an Appeal court sitting in Abuja, Nigeria sacked Alfa unjustly and replaced him with Atai Aidoko Ali as a senator representing Kogi East Senatorial.
However after a successful court case Isaac Alfa returned to the senatorial role after Aidoko was denied by the supreme court.