Francisco Moreno Domagoso (colloquially named as Yorme Isko) (born October 24, 1974) is a Filipino former actor and a current politician.
He is the 27th mayor and a former Vice Mayor of the City of Manila, the capital city of the Philippines; and a former three-term councilor of the city's first congressional district.
He is also a former actor, using the screen name Isko Moreno, who started as a matinee idol and later became known for his mature roles during his short stint in the "Titillating Films" genre that was prevalent in the country during the 1990s.