Ismenia Villalba (Pampatar, Nueva Esparta, September 18, 1929 – Caracas, September 19, 2009), was a Venezuelan politician, wife of Jóvito Villalba.
Ismenia Villalba served as deputy for Caracas and Nueva Esparta and was the first woman that participates in a Presidential Election in Venezuela, representing the Unión Republicana Democrática in the 1988 election.