William Tuke (24 March 1732 – 6 December 1822) was an English businessman, philanthropist and Quaker, instrumental in developing more humane methods in the custody and care of people with mental disorders using "gentler" methods, an approach that came to be known as moral treatment.
He was a major figure in founding The Retreat at Lamel Hill in York as a place for treating mental-health needs.
Tuke and his wife Esther Maud supported stricter adherence to Quaker principles.
He was an abolitionist, a patron of the Bible Society, and a vocal opponent of the East India Company's inhumane practices.