John Beirne Snr (1 April 1893 – date of death unknown) was an Irish Clann na Talmhan politician.
A shopkeeper and farmer, Beirne was first elected to Dáil Éireann at the 1943 general election as a Clann na Talmhan Teachta Dála (TD) for the Roscommon constituency and he was re-elected at the 1944 general election.His son John Beirne Jnr also served as a Clann na Talmhan TD for Roscommon from 1948 to 1961.