John David Spence (born November 10, 1944) is a Canadian medical doctor, medical researcher and professor at the University of Western Ontario.
Along with his affiliation with the University of Western Ontario (where he teaches Clinical Neurological Science) he is affiliated with the London Health Sciences Centre's University Hospital (where he has set up and runs stroke prevention clinics) and the Robarts Research Institute, one of Canada's leading medical research organizations.
He is a recognized expert in stroke prevention and stroke prevention research and has over 500 peer-reviewed publications since 1970.
He has delivered more than 600 lectures in 38 countries to physicians around the world.
In 2015, he received the Research Excellence Award from the Canadian Society for Atherosclerosis, Thrombosis and Vascular Biology.
In 2019, he was appointed a Member of the Order of Canada.
Dr.
Spence is the director of the Stroke Prevention & Atherosclerosis Research Centre (SPARC), a unit of the Robarts Research Institute.
With Maria Dicicco, RVT, he pioneered the measurement of total plaque area (TPA) in a patient's carotid artery using ultrasound technology.
The ability to measure TPA gives doctors the ability to treat, and measure the change in, the amount of plaque in a patient's arteries and has given researchers the ability to measure the effectiveness of new drug treatment therapies for stroke prevention.
in high-risk patients with narrowing of the carotid arteries, the process of "Treating Arteries" was associated with a >80% reduction in the 2-year risk of strokes and heart attacks.
doi: 10.1001/archneurol.2009.289.
PubMed PMID: 20008646 Dr.
Spence is recognized as "The Father of Total Plaque Area Measurement" and the importance of TPA measurement is that, in Dr Spence's words, "We can now treat arteries instead of just treating risk factors".