Ann Silver (born 23 November 1929) is an eminent British physiologist, known for her pioneering work on the neurotransmitter acetylcholine.
She wrote a seminal text on the Biology of cholinesterases in 1974 and helped to lay the foundations of the cholinergic hypothesis by mapping cholinergic systems and helping to emphasise the importance of these pathways in brain areas central to cognitive and memory functions, leading to the use of cholinesterase inhibitors in the treatment of Alzheimer's disease.