She is Dr Lee's Professor of Anatomy at the University of Oxford and a Fellow of Hertford College, Oxford.
She is director of the Medical Research Council (MRC) functional genetics unit, a governor of the Wellcome Trust, a director of the Oxford Centre for Gene Function, and a patron and Senior Member of Oxford University Scientific Society.
Her research group has an international reputation for work on Duchenne muscular dystrophy (DMD).
In the 1980s, she developed a test which allowed for the screening of foetuses whose mothers have a high risk of carrying DMD.