Lee Jesse Gamble (September 15, 1910 – August 21, 1994) was a professional baseball player.
He was an outfielder over parts of four seasons (1935, 1938–40) with the Cincinnati Reds.
For his career, he compiled a .266 batting average in 342 at-bats, with 21 runs batted in.
He was born in Renovo, Pennsylvania and later died in Punxsutawney, Pennsylvania at the age of 84.