Hubert Leonard Spence (May 23, 1909 – November 10, 1947) was a swimmer from British Guiana (present-day Guyana) who competed for Bermuda in the 1936 Summer Olympics.
In 1933, the three brothers Leonard, Wallace and Walter Spence won the 3×100 medley relay at the Amateur Athletic Union (AAU) championships – the only such feat in the AAU history.
Later, they set a world record in this event.
Leonard participated in the 1936 Summer Olympics in the 100 m freestyle, 200 m breaststroke and 4 × 200 m freestyle events, but did not reach the finals.
In 1967, the Spence brothers were inducted to the International Swimming Hall of Fame.