Leopold Rügheimer (May 5, 1850 – May 24, 1917) was a notable German chemist whose name is connected to the Staedel-Rugheimer pyrazine synthesis, a reaction that was discovered by himself and Wilhelm Staedel.
Rügheimer was born in Walldorf (near Meiningen) in 1850 as the son of a merchant.
He studied at the universities of Leipzig, Würzburg and Tübingen.
He died in Kiel in 1917 after a successful academic career.