She was born in Lucca, daughter of the nobleman Sebastiano Motroni-Andreozzi and his wife Eleonora Flekestein.She studied counterpoint with Domenico Quilici and was admitted to the Accademia Filarmonica in Bologna in 1820 as an 'honorary master composer'.
In 1823 she married the Marquis Lorenzo Bottini, a prominent political figure.
She was one of the few women whose music was played for the traditional festival in honor of St.