Michèle de Saint Laurent (December 9, 1926 – July 11, 2003) was a French carcinologist.
She spent most of her career at the Muséum national d'histoire naturelle in Paris, working on the systematics of decapod crustaceans; her major contributions were to hermit crabs and Thalassinidea, and she also co-described Neoglyphea, a living fossil discovered in 1975.