Syedna Mohammed Burhanuddin (6 March 1915 – 17 January 2014) was the 52nd Da'i al-Mutlaq of Dawoodi Bohras, a subgroup within the Mustaali, Ismaili Shia branch of Islam.
He was appointed as the 52nd Da'i al-Mutlaq at the age of 52 in 1967.
He was the longest living Da'i al-Mutlaq of the Dawoodi Bohra community.
Compared to those of his predecessor, Syedna Burhanuddin's policies were aimed at Islamization of his sect.Syedna Burhanuddin was presented the highest national civic honors by the leaders of Egypt and Jordan.
He was the first Da'i al-Mutlaq to visit Europe and America.